| 2. Ronde | 31.07.2021 | FK Pohronie | - | MFK Zemplín Michalovce | 2:0 | ||||
| 3. Ronde | 08.08.2021 | MŠK Žilina | - | FK Pohronie | 3:1 | ||||
| 7. Ronde | 11.09.2021 | FK Senica | - | FK Pohronie | 1:0 | ||||
| 8. Ronde | 18.09.2021 | Tatran Liptovský Mikuláš | - | FK Pohronie | 5:1 | ||||
| 17. Ronde | 04.12.2021 | FC DAC 1904 | - | FK Pohronie | 2:0 | ||||
| 18. Ronde | 11.12.2021 | FK Pohronie | - | FK Senica | 0:1 | ||||
| 19. Ronde | 18.12.2021 | FK Pohronie | - | Tatran Liptovský Mikuláš | 2:2 | ||||
| 20. Ronde | 12.02.2022 | AS Trenčín | - | FK Pohronie | 3:0 | ||||
| 21. Ronde | 19.02.2022 | FK Pohronie | - | Slovan Bratislava | 3:4 | ||||
| 22. Ronde | 26.02.2022 | MFK Ružomberok | - | FK Pohronie | 1:0 |
Slowakije