| 2. Ronde | 10.02.2018 | Rampla Juniors | - | Nacional | 0:3 |  |
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| 6. Ronde | 10.03.2018 | Nacional | - | Defensor Sporting | 2:0 | ||||
| 7. Ronde | 22.03.2018 | Racing | - | Nacional | 0:1 | |
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| 8. Ronde | 25.03.2018 | Nacional | - | River Plate | 1:0 | ||||
| 10. Ronde | 31.03.2018 | Nacional | - | Liverpool | 0:0 | ||||
| 12. Ronde | 15.04.2018 | Nacional | - | Boston River | 1:0 |  |
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| 13. Ronde | 22.04.2018 | Peñarol | - | Nacional | 1:1 | ||||
| 14. Ronde | 28.04.2018 | Nacional | - | Atenas | 2:1 | |
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| 15. Ronde | 05.05.2018 | Danubio | - | Nacional | 1:2 | |
Uruguay