| 2. Ronde | 09.07.2022 | Deportivo Guadalajara [U18] | - | Atlético San Luis [U18] | 3:1 | ||||
| 4. Ronde | 20.07.2022 | Deportivo Guadalajara [U18] | - | Club León [U18] | 2:2 | ||||
| 5. Ronde | 27.07.2022 | Gallos Blancos [U18] | - | Deportivo Guadalajara [U18] | 0:1 | ||||
| 6. Ronde | 30.07.2022 | Deportivo Guadalajara [U18] | - | CF Pachuca [U18] | 0:1 | ||||
| 7. Ronde | 05.08.2022 | Mazatlán FC [U18] | - | Deportivo Guadalajara [U18] | 2:2 |  |
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| 8. Ronde | 13.08.2022 | Deportivo Guadalajara [U18] | - | Atlas Guadalajara [U18] | 0:1 | ||||
| 12. Ronde | 04.09.2022 | Deportivo Toluca [U18] | - | Deportivo Guadalajara [U18] | 1:0 | ||||
| 13. Ronde | 07.09.2022 | Club Tijuana [U18] | - | Deportivo Guadalajara [U18] | 1:0 | ||||
| 14. Ronde | 10.09.2022 | Deportivo Guadalajara [U18] | - | Puebla FC [U18] | 1:1 | ||||
| 16. Ronde | 28.09.2022 | Deportivo Guadalajara [U18] | - | CF Monterrey [U18] | 4:0 | ||||
| 17. Ronde | 01.10.2022 | Cruz Azul [U18] | - | Deportivo Guadalajara [U18] | 0:4 |
Mexico