| 3. Ronde | 22.01.2022 | AD San Carlos | - | Municipal Pérez Zeledón | 1:1 | ||||
| 4. Ronde | 04.02.2022 | Municipal Pérez Zeledón | - | LD Alajuelense | 2:1 | ||||
| 5. Ronde | 09.02.2022 | AD Guanacasteca | - | Municipal Pérez Zeledón | 0:0 | ||||
| 6. Ronde | 13.02.2022 | Santos de Guápiles | - | Municipal Pérez Zeledón | 0:1 | ||||
| 7. Ronde | 20.02.2022 | Municipal Pérez Zeledón | - | Deportivo Saprissa | 0:0 |  |
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| 8. Ronde | 26.02.2022 | Sporting FC | - | Municipal Pérez Zeledón | 1:1 | ||||
| 9. Ronde | 03.03.2022 | Municipal Pérez Zeledón | - | Guadalupe | 0:1 | |
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| 13. Ronde | 11.04.2022 | Municipal Pérez Zeledón | - | CS Cartaginés | 3:0 | ||||
| 15. Ronde | 20.04.2022 | LD Alajuelense | - | Municipal Pérez Zeledón | 3:1 | ||||
| 17. Ronde | 27.04.2022 | Municipal Pérez Zeledón | - | Santos de Guápiles | 1:1 | ||||
| 18. Ronde | 02.05.2022 | Deportivo Saprissa | - | Municipal Pérez Zeledón | 2:1 |
Costa Rica
Panama