| 21. Ronde | 28.01.2022 | Arema Cronus FC | - | Persipura Jayapura | 1:0 | ||||
| 23. Ronde | 06.02.2022 | Persebaya Surabaya | - | Persipura Jayapura | 0:2 | ||||
| 24. Ronde | 10.02.2022 | Persipura Jayapura | - | Persik Kediri | 0:0 | ||||
| 25. Ronde | 14.02.2022 | PS Barito Putera | - | Persipura Jayapura | 3:0 | ||||
| 26. Ronde | 18.02.2022 | Persipura Jayapura | - | Persib Bandung | 0:3 | ||||
| 27. Ronde | 24.02.2022 | Bali United | - | Persipura Jayapura | 4:1 | ||||
| 28. Ronde | 28.02.2022 | Persipura Jayapura | - | Borneo FC | 2:1 | ||||
| 29. Ronde | 05.03.2022 | Persikabo 1973 | - | Persipura Jayapura | 1:1 |  |
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| 30. Ronde | 10.03.2022 | Persipura Jayapura | - | PSM Makassar | 0:0 | |
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| 31. Ronde | 16.03.2022 | Bhayangkara Presisi Indonesia | - | Persipura Jayapura | 1:2 | ||||
| 33. Ronde | 24.03.2022 | PSIS Semarang | - | Persipura Jayapura | 0:4 | ||||
| 34. Ronde | 31.03.2022 | Persita Tangerang | - | Persipura Jayapura | 0:3 |
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