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| 05.02.2016 | 18:30 | VfL Bochum | - | SC Freiburg | 2:0 (1:0) | |
| 18:30 | SV Sandhausen | - | SC Paderborn 07 | 1:0 (0:0) | ||
| 18:30 | 1. FC Kaiserslautern | - | 1. FC Union Berlin | 2:2 (2:0) | ||
| 06.02.2016 | 13:00 | TSV 1860 München | - | 1. FC Nürnberg | 0:1 (0:1) | |
| 13:00 | Fortuna Düsseldorf | - | 1. FC Heidenheim 1846 | 0:1 (0:0) | ||
| 07.02.2016 | 13:30 | RB Leipzig | - | Eintracht Braunschweig | 2:0 (2:0) | |
| 13:30 | SpVgg Greuther Fürth | - | FC St. Pauli | 0:2 (0:1) | ||
| 13:30 | Karlsruher SC | - | FSV Frankfurt | 1:1 (0:0) | ||
| 08.02.2016 | 20:15 | Arminia Bielefeld | - | MSV Duisburg | 2:1 (2:1) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
RB Leipzig | 20 | 13 | 5 | 2 | 33:18 | 15 | 44 |
| 2 |
|
SC Freiburg | 20 | 11 | 5 | 4 | 43:24 | 19 | 38 |
| 3 |
|
1. FC Nürnberg | 20 | 10 | 6 | 4 | 39:27 | 12 | 36 |
| 4 |
|
FC St. Pauli | 20 | 9 | 6 | 5 | 24:20 | 4 | 33 |
| 5 |
|
VfL Bochum | 20 | 8 | 7 | 5 | 30:18 | 12 | 31 |
| 6 |
|
Eintracht Braunschweig | 20 | 8 | 5 | 7 | 27:17 | 10 | 29 |
| 7 |
|
SV Sandhausen | 20 | 9 | 5 | 6 | 28:23 | 5 | 29 |
| 8 |
|
1. FC Heidenheim 1846 | 20 | 7 | 6 | 7 | 22:20 | 2 | 27 |
| 9 |
|
Arminia Bielefeld | 20 | 5 | 12 | 3 | 19:17 | 2 | 27 |
| 10 |
|
1. FC Kaiserslautern | 20 | 7 | 6 | 7 | 26:26 | 0 | 27 |
| 11 |
|
Karlsruher SC | 20 | 7 | 5 | 8 | 20:26 | -6 | 26 |
| 12 |
|
SpVgg Greuther Fürth | 20 | 7 | 4 | 9 | 25:34 | -9 | 25 |
| 13 |
|
1. FC Union Berlin | 20 | 5 | 9 | 6 | 33:32 | 1 | 24 |
| 14 |
|
FSV Frankfurt | 20 | 6 | 5 | 9 | 19:28 | -9 | 23 |
| 15 |
|
Fortuna Düsseldorf | 20 | 5 | 5 | 10 | 15:25 | -10 | 20 |
| 16 |
|
SC Paderborn 07 | 20 | 4 | 5 | 11 | 17:34 | -17 | 17 |
| 17 |
|
TSV 1860 München | 20 | 2 | 8 | 10 | 15:27 | -12 | 14 |
| 18 |
|
MSV Duisburg | 20 | 2 | 6 | 12 | 16:35 | -19 | 12 |
| Promotie | |
| Promotie en degradatie | |
| Promotie en degradatie | |
| Degradatie |
