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| 29.03.2019 | 18:30 | FC St. Pauli | - | MSV Duisburg | 0:0 (0:0) | |
| 18:30 | 1. FC Magdeburg | - | 1. FC Heidenheim 1846 | 0:0 (0:0) | ||
| 30.03.2019 | 13:00 | VfL Bochum | - | Hamburger SV | 0:0 (0:0) | |
| 13:00 | SV Darmstadt 98 | - | Jahn Regensburg | 1:1 (0:0) | ||
| 13:00 | 1. FC Union Berlin | - | SC Paderborn 07 | 1:3 (0:1) | ||
| 31.03.2019 | 13:30 | 1. FC Köln | - | Holstein Kiel | 4:0 (2:0) | |
| 13:30 | SpVgg Greuther Fürth | - | Arminia Bielefeld | 2:2 (2:0) | ||
| 13:30 | FC Ingolstadt 04 | - | SV Sandhausen | 1:2 (1:0) | ||
| 01.04.2019 | 20:30 | Erzgebirge Aue | - | Dynamo Dresden | 1:3 (1:0) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
1. FC Köln | 27 | 17 | 4 | 6 | 72:35 | 37 | 55 |
| 2 |
|
Hamburger SV | 27 | 15 | 6 | 6 | 38:29 | 9 | 51 |
| 3 |
|
1. FC Union Berlin | 27 | 12 | 11 | 4 | 43:26 | 17 | 47 |
| 4 |
|
SC Paderborn 07 | 27 | 12 | 8 | 7 | 61:41 | 20 | 44 |
| 5 |
|
FC St. Pauli | 27 | 13 | 5 | 9 | 38:40 | -2 | 44 |
| 6 |
|
1. FC Heidenheim 1846 | 27 | 11 | 10 | 6 | 40:32 | 8 | 43 |
| 7 |
|
Holstein Kiel | 27 | 11 | 9 | 7 | 51:41 | 10 | 42 |
| 8 |
|
Jahn Regensburg | 27 | 9 | 11 | 7 | 39:39 | 0 | 38 |
| 9 |
|
VfL Bochum | 27 | 9 | 8 | 10 | 37:39 | -2 | 35 |
| 10 |
|
Arminia Bielefeld | 27 | 9 | 8 | 10 | 40:43 | -3 | 35 |
| 11 |
|
SpVgg Greuther Fürth | 27 | 8 | 10 | 9 | 28:43 | -15 | 34 |
| 12 |
|
SV Darmstadt 98 | 27 | 9 | 6 | 12 | 38:46 | -8 | 33 |
| 13 |
|
Erzgebirge Aue | 27 | 9 | 5 | 13 | 34:38 | -4 | 32 |
| 14 |
|
Dynamo Dresden | 27 | 8 | 8 | 11 | 32:39 | -7 | 32 |
| 15 |
|
SV Sandhausen | 27 | 6 | 8 | 13 | 31:39 | -8 | 26 |
| 16 |
|
1. FC Magdeburg | 27 | 4 | 12 | 11 | 28:41 | -13 | 24 |
| 17 |
|
MSV Duisburg | 27 | 5 | 8 | 14 | 28:46 | -18 | 23 |
| 18 |
|
FC Ingolstadt 04 | 27 | 4 | 7 | 16 | 26:47 | -21 | 19 |
| Promotie | |
| Promotie en degradatie | |
| Promotie en degradatie | |
| Degradatie |
