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| 15.01.2021 | 18:00 | FK Teplice | - | FK Jablonec | 0:5 (0:3) | |
| 16.01.2021 | 14:00 | FK Mladá Boleslav | - | Zbrojovka Brno | 1:1 (0:1) | |
| 14:00 | SFC Opava | - | FC Fastav Zlín | 0:0 (0:0) | ||
| 16:00 | 1. FC Slovácko | - | MFK Karviná | 2:0 (0:0) | ||
| 16:00 | Slovan Liberec | - | Bohemians Praha 1905 | 1:1 (1:0) | ||
| 18:30 | Slavia Praag | - | Sigma Olomouc | 3:1 (2:1) | ||
| 17.01.2021 | 14:00 | FK Pardubice | - | Dynamo České Budějovice | 0:2 (0:1) | |
| 16:00 | 1. FK Příbram | - | Viktoria Plzeň | 0:0 (0:0) | ||
| 18:30 | Baník Ostrava | - | Sparta Praag | 0:0 (0:0) |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Slavia Praag | 15 | 13 | 2 | 0 | 45:7 | 38 | 41 |
| 2 |
|
FK Jablonec | 15 | 10 | 2 | 3 | 31:15 | 16 | 32 |
| 3 |
|
Sparta Praag | 15 | 10 | 2 | 3 | 32:18 | 14 | 32 |
| 4 |
|
1. FC Slovácko | 15 | 8 | 3 | 4 | 27:16 | 11 | 27 |
| 5 |
|
Baník Ostrava | 15 | 7 | 4 | 4 | 20:12 | 8 | 25 |
| 6 |
|
Slovan Liberec | 15 | 6 | 4 | 5 | 21:17 | 4 | 22 |
| 7 |
|
Sigma Olomouc | 15 | 5 | 7 | 3 | 21:18 | 3 | 22 |
| 8 |
|
FK Pardubice | 15 | 6 | 4 | 5 | 15:17 | -2 | 22 |
| 9 |
|
Viktoria Plzeň | 15 | 6 | 3 | 6 | 28:21 | 7 | 21 |
| 10 |
|
Dynamo České Budějovice | 15 | 5 | 6 | 4 | 21:23 | -2 | 21 |
| 11 |
|
MFK Karviná | 15 | 5 | 5 | 5 | 14:20 | -6 | 20 |
| 12 |
|
FC Fastav Zlín | 15 | 5 | 2 | 8 | 17:23 | -6 | 17 |
| 13 |
|
Bohemians Praha 1905 | 15 | 4 | 4 | 7 | 17:19 | -2 | 16 |
| 14 |
|
FK Teplice | 15 | 5 | 1 | 9 | 16:33 | -17 | 16 |
| 15 |
|
FK Mladá Boleslav | 15 | 2 | 4 | 9 | 17:29 | -12 | 10 |
| 16 |
|
Zbrojovka Brno | 15 | 2 | 4 | 9 | 13:28 | -15 | 10 |
| 17 |
|
1. FK Příbram | 15 | 2 | 4 | 9 | 11:30 | -19 | 10 |
| 18 |
|
SFC Opava | 15 | 1 | 5 | 9 | 10:30 | -20 | 8 |
| Champions League Kwali. | |
| Europa League Kwali. | |
| Degradatie |
