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| U | Lazio | - | Inter | 1:1 (1:1) | ||
| R | Inter | - | Lazio | 1:0 (1:0) | ||
| U: 24.01.2006 21:00 | R: 02.02.2006 21:00 | Winnaars: Inter | ||||
| U | Udinese Calcio | - | Sampdoria | 1:1 (1:0) | ||
| R | Sampdoria | - | Udinese Calcio | 2:2 (0:1) | ||
| U: 25.01.2006 18:00 | R: 01.02.2006 17:30 | Winnaars: Udinese Calcio | ||||
| U | AC Milan | - | US Palermo | 1:0 (0:0) | ||
| R | US Palermo | - | AC Milan | 3:0 (2:0) | ||
| U: 25.01.2006 21:00 | R: 31.01.2006 21:00 | Winnaars: US Palermo | ||||
| U | Juventus | - | AS Roma | 2:3 (0:1) | ||
| R | AS Roma | - | Juventus | 0:1 (0:0) | ||
| U: 26.01.2006 21:00 | R: 01.02.2006 21:00 | Winnaars: AS Roma | ||||
