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| 13.08.2022 | 16:00 | CF Pachuca | - | FC Juárez | 3:1 (3:0) | |
| 17:00 | Mazatlán FC | - | Club León | 3:0 (0:0) | ||
| 18:30 | Club Necaxa | - | Puebla FC | 1:0 (1:0) | ||
| 18:30 | Deportivo Toluca | - | Cruz Azul | 3:3 (2:2) | ||
| 18:30 | Santos Laguna | - | UANL Tigres | 2:2 (2:0) | ||
| 18:30 | Pumas UNAM | - | CF América | 3:0 (1:0) | ||
| 18:30 | CF Monterrey | - | Club Tijuana | 3:2 (1:1) | ||
| 18:45 | Atlético San Luis | - | Deportivo Guadalajara | 2:1 (0:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| 1 | |||||||||
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Pumas UNAM | 7 | 6 | 1 | 0 | 17:9 | 8 | 19 |
| 2 |
|
Deportivo Toluca | 7 | 4 | 3 | 0 | 16:9 | 7 | 15 |
| 3 |
|
Club Necaxa | 7 | 4 | 0 | 3 | 14:5 | 9 | 12 |
| 4 |
|
CF Pachuca | 7 | 3 | 2 | 2 | 9:5 | 4 | 11 |
| 5 |
|
Cruz Azul | 7 | 3 | 1 | 3 | 16:16 | 0 | 10 |
| 6 |
|
Gallos Blancos | 7 | 2 | 2 | 3 | 11:9 | 2 | 8 |
| 7 |
|
CF América | 7 | 2 | 1 | 4 | 10:15 | -5 | 7 |
| 8 |
|
Puebla FC | 7 | 2 | 0 | 5 | 9:15 | -6 | 6 |
| 9 |
|
FC Juárez | 8 | 1 | 0 | 7 | 11:30 | -19 | 3 |
| 2 | |||||||||
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CF Monterrey | 8 | 5 | 3 | 0 | 22:10 | 12 | 18 |
| 2 |
|
Club Tijuana | 7 | 5 | 1 | 1 | 19:6 | 13 | 16 |
| 3 |
|
Atlas Guadalajara | 7 | 4 | 3 | 0 | 21:7 | 14 | 15 |
| 4 |
|
Deportivo Guadalajara | 7 | 3 | 0 | 4 | 7:10 | -3 | 9 |
| 5 |
|
Santos Laguna | 7 | 2 | 2 | 3 | 19:14 | 5 | 8 |
| 6 |
|
UANL Tigres | 7 | 2 | 2 | 3 | 11:17 | -6 | 8 |
| 7 |
|
Club León | 7 | 2 | 1 | 4 | 8:10 | -2 | 7 |
| 8 |
|
Atlético San Luis | 7 | 2 | 0 | 5 | 8:28 | -20 | 6 |
| 9 |
|
Mazatlán FC | 7 | 1 | 0 | 6 | 8:21 | -13 | 3 |
| Play-offs | |
| Play-offs |
