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| 26.03.2022 | 15:00 | FC Sion II | - | FC Basel 1893 II | 1:2 (0:1) | |
| 16:00 | FC Rapperswil-Jona | - | FC Black Stars Basel | 0:0 (0:0) | ||
| 16:00 | SC Cham | - | FC Bavois | 1:1 (0:1) | ||
| 16:00 | SC Brühl | - | AC Bellinzona | 0:1 (0:1) | ||
| 16:00 | SC YF/Juventus Zürich | - | FC Stade Nyonnais | 0:2 (0:1) | ||
| 16:00 | FC Breitenrain Bern | - | BSC Young Boys II | 1:2 (1:2) | ||
| 16:00 | FC Zürich II | - | FC Chiasso | 1:1 (0:0) | ||
| 17:00 | Etoile Carouge FC | - | FC Biel/Bienne | 2:0 (0:0) |
| » Stand | Thuis | uit | Heenronde | Returnronde |
| # | Team | GS. | W. | G. | V. | Dp. | Ds. | P. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
FC Breitenrain Bern | 24 | 17 | 6 | 1 | 48:19 | 29 | 57 |
| 2 |
|
AC Bellinzona | 24 | 15 | 4 | 5 | 46:26 | 20 | 49 |
| 3 |
|
FC Stade Nyonnais | 24 | 14 | 4 | 6 | 56:32 | 24 | 46 |
| 4 |
|
FC Chiasso | 24 | 12 | 7 | 5 | 43:25 | 18 | 43 |
| 5 |
|
FC Zürich II | 24 | 9 | 9 | 6 | 36:25 | 11 | 36 |
| 6 |
|
SC Cham | 24 | 9 | 7 | 8 | 37:37 | 0 | 34 |
| 7 |
|
BSC Young Boys II | 24 | 9 | 6 | 9 | 40:40 | 0 | 33 |
| 8 |
|
FC Bavois | 24 | 9 | 6 | 9 | 34:36 | -2 | 33 |
| 9 |
|
Etoile Carouge FC | 24 | 8 | 8 | 8 | 27:32 | -5 | 32 |
| 10 |
|
FC Rapperswil-Jona | 24 | 8 | 7 | 9 | 32:37 | -5 | 31 |
| 11 |
|
FC Black Stars Basel | 24 | 7 | 8 | 9 | 27:36 | -9 | 29 |
| 12 |
|
FC Biel/Bienne | 24 | 7 | 5 | 12 | 33:40 | -7 | 26 |
| 13 |
|
SC YF/Juventus Zürich | 24 | 6 | 5 | 13 | 33:44 | -11 | 23 |
| 14 |
|
FC Basel 1893 II | 24 | 6 | 4 | 14 | 41:60 | -19 | 22 |
| 15 |
|
SC Brühl | 24 | 4 | 5 | 15 | 30:47 | -17 | 17 |
| 16 |
|
FC Sion II | 24 | 4 | 5 | 15 | 28:55 | -27 | 17 |
| Play-offs | |
| Play-offs | |
| Promotie en degradatie |
